Infusion is directly injected into a large number of human veins, in the whole process of infusion production on the process and quality control is very strict, so its production equipment must meet the requirements, bottle washing machine is one of the main equipment of infusion filling production line. The performance of bottle washing machine has a direct impact on the bottle washing degree, production efficiency, bottle shape adaptation and production cost. The research and development of new bottle washing machine has become a very concerned topic in the pharmaceutical machinery industry.

Research status and development trend at home and abroad

Current situation of foreign research

At present, foreign bottle washing machine (hereinafter referred to as "reference machine") applied photoelectric, electrical protection, photoelectric sensing detection, frequency conversion stepless speed regulation, programmable control and other new technologies. The machine, electricity, instrument integration degree is high, the structure is compact, reasonable, the material choice is balanced appropriate, the use is safe and reliable, is advantageous to the GMP implementation. However, the bottle washing process of the reference machine is not suitable for most of the domestic glass, and its cleaning effect is not ideal, the main reason is the heavy pollution of the glass bottles being washed; Secondly, the machine only USES distilled water to wash the inside and outside of the glass bottle.

The current situation of domestic development

There are many types of bottle washing machines used in domestic infusion plants, and each has its own characteristics, which can be divided into the following types:

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This machine is a semi - mechanical, semi - manual bottle washing machine

Shoe type bottle washer

This machine adopts the clearance movement of shoes, and there are two pairs of pneumatic manipulator to load and unload the glass bottle before and after, so that the glass bottle is always facing down in the washing station, so as to facilitate the cleaning effect of washing the bottle. Deficiency is coarse, fine wash can not be isolated, low production capacity, and debugging has a certain degree of difficulty, has been phased out.

Cylinder bottle washer

This machine is characterized by mature bottle washing technology, the production capacity is suitable for China's national conditions, and suitable for acid and alkali washing two processes. The washing effect is reliable, the machine result is simple, the manufacture, the debugging is convenient, the rough, the fine washing may separate, is a kind of rudiment which the foreign large-scale crawler bottle carrier type washes the bottle machine. The disadvantage of this method is that it has strict requirements on the geometric dimensions of glass bottles. The second is that there are traces of residual liquid in the glass bottle after each washing process.

Van heresy in and out of the bottle washer

This machine has high automaticity, it can clean the bottle automatically and continuously with the functions of lye, hot water, brush and distilled water. This machine combines the requirements of GMP infusion production, so that the bottle into and out of the bottle at both ends of the body, to prevent cross-contamination.

The development trend of domestic research

Increasingly to the development of high-grade pharmaceutical machinery, will inevitably promote the improvement of bottle washing machine. Several domestic pharmaceutical plants producing infusion equipment are actively planning to launch a new generation of bottle washing machines. The new generation of bottle washer will enhance the adaptability to the status quo and reduce the sensitivity to glass bottles. For the application of new technology will shorten the gap with the reference machine, and take into account the reality of domestic components and maintenance level and other factors. At the same time, "pneumatic", "hydraulic" to simplify the mechanical structure, reduce costs, in order to shorten the cycle of equipment upgrading. Based on the particularity of infusion equipment, it is necessary to make a breakthrough in the integration of machine, electricity and instrument, so as to make the equipment more in line with the requirements of "GMP" and ensure product quality.